A review of the pharmacological aspects of Solanum nigrum Linn.

Citation:

Atanu FO, Ebiloma UG, Ajayi EI. A review of the pharmacological aspects of Solanum nigrum Linn. Biotechnol. Mol. Biol. Rev. (BMBR) [Internet]. 2011;6(1):1-7.

Abstract:

This article reviews, bridges the gap between the folkloric use of Solanum nigrum Linn. (Sn) and the results of evidence based experiments. Although Sn is a rich source of one of plants most dreaded toxins solanine, it has appreciably demonstrated its potential as a reservoir of antioxidants having hepatoprotective, anti-tumor, cytostatic, anti-convulsant, anti-ulcerogenic and anti-inflammatory effects. The review encompasses in vitro, in vivo and clinical studies done on Sn, while examining whether or not correct scientific measures have been taken in generating experimental evidences for its traditional uses. This review would afford research scientist to know how much is known and what is left undone in the investigation of Sn.

Key words: Solanum nigrum, folklore medicine, anticancer, solanine.

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