@article {205,
	title = {Analgesic potential of certain traditional African herbal extracts in high fat diet-manipulated hyperglycaemic rats},
	journal = {Ife J. Sc. (IJS)},
	volume = {17},
	year = {2015},
	pages = {511-517},
	abstract = {In this study, an assessment of the analgesic potential of\&nbsp;Zea mays L.,\&nbsp;Nauclea latifolia\&nbsp;Sm leaf; leaf and stalk of\&nbsp;Manihot esculenta\&nbsp;Crantz was made. Pain was induced by 0.6\% acetic acid in high fat diet-manipulated,\&nbsp; alloxaninduced hyperglycaemic rats. Paracetamol{\textregistered} (65 mg/kgBW) served as positive control, while olive oil was used as negative control. Test groups were administered ethyl acetate extracts of the traditional African herbal extracts (TAHE) at a dose of 50 mg/kgBW. All interventions were administered as a single dose by oral gavage. Analgesic activity was measured by counting the percentage of writhing movements as a measure of alleviation of visceral pain by each intervention. The results showed that ethyl acetate extract of\&nbsp;Zea mays L. and\&nbsp;Nauclea latifolia\&nbsp;Smith leaf,\&nbsp;Manihot esculenta\&nbsp;Crantz leaf and stalk had peripheral analgesic activities of 53.27 \%, 55.71\%, 69.02\% and 60.73\% respectively as compared to Paracetamol{\textregistered} (57.32\%).},
	url = {https://www.ajol.info/index.php/ijs/article/view/131736/121337},
	author = {E. I. O. Ajayi and E. T. Ogungbuji and G. Nojeem}
}
