<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">O. R. Molehin</style></author><author><style face="normal" font="default" size="100%">E. I. O. Ajayi</style></author><author><style face="normal" font="default" size="100%">A. F. Attah</style></author><author><style face="normal" font="default" size="100%">O. R. Awope</style></author><author><style face="normal" font="default" size="100%">E. T. Ige</style></author><author><style face="normal" font="default" size="100%">O. E. Omotoyinbo</style></author><author><style face="normal" font="default" size="100%">B. J. Aladetuyi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The effects of solvent extracts of&lt;em&gt;Citrullus&lt;/em&gt;&lt;em&gt;lanatus&lt;/em&gt;seeds and&lt;em &gt;Chrysophyllum&lt;/em&gt;&lt;em &gt;albidum&lt;/em&gt;cotyledons on rat hepatocyte regeneration, cytochrome c oxidaseactivities and bacteriocin- producing gram-negative bacteria</style></title><secondary-title><style face="normal" font="default" size="100%">PharmacologyOnLine</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://pharmacologyonline.silae.it/files/archives/2019/vol3/PhOL_2019_3_A015_Molehin.pdf</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">3</style></volume><pages><style face="normal" font="default" size="100%">165-184</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Medicinal plants have been shown to exert a plethora of biological and pharmacological which has&amp;nbsp;been associated with the presence of several bioactive components. In this study, the effects of crude&amp;nbsp;extracts of &lt;em style=&quot;font-size: initial;&quot;&gt;Citrullus lanatus&lt;/em&gt; seeds (CACL) and &lt;em style=&quot;font-size: initial;&quot;&gt;Chrysophyllum albidum&lt;/em&gt; cotyledons (CACA) on rat&amp;nbsp;hepatocyte regeneration, liver cytochrome c oxidase activities, and their antimicrobial properties on a&amp;nbsp;few bacteriocin-producing Gram-negative bacteria were determined. CACL and CACA were screened&amp;nbsp;for the presence of amino acids using TLC sprayed with ninhydrin, pyridine and modified Commassie&amp;nbsp;brilliant blue (G250). The amino acids were elucidated by Gas Chromatography-Mass Spectrometry&amp;nbsp;(GC/MS) and Fourier-transform infrared spectroscopy (FTIR). CACA enhanced tissue regeneration in rat&amp;nbsp;hepatocytes, in situ and increased the collagen content. CACA also enhanced the activity cytochrome c&amp;nbsp;oxidase in the liver mitochondrial portion, but inhibited same in the homogenate. CACA and CACL did&amp;nbsp;not inhibit the bacteriocin-producing bacteria at the different concentrations tested. It is evident that&amp;nbsp;CACA and CACL contain amino acids that can improve liver antioxidant functions and its mitochondrial&amp;nbsp;electron transport. Both amino acid-rich fractions, combined with bacteriocin may accelerate aseptic&amp;nbsp;wound healing.&lt;/p&gt;
&lt;p&gt;&lt;br&gt;Keywords: Tissue regeneration, catalase, cytochrome c oxidase, seed amino acids, &lt;em&gt;Citrullus lanatus&lt;/em&gt; seeds, &lt;em&gt;Chrysophyllum albidum&lt;/em&gt; cotyledons, bacteriocin-producing bacteria.&lt;/p&gt;</style></abstract></record></records></xml>