<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">E. I. O. Ajayi</style></author><author><style face="normal" font="default" size="100%">A. Agarwal</style></author><author><style face="normal" font="default" size="100%">U. C. Banerjee</style></author><author><style face="normal" font="default" size="100%">O. O. Olorunsogo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Ethanol extract of Manihot esculenta leaf: A potential source of antioxidant, xanthine oxidase and lipase inhibitors</style></title><secondary-title><style face="normal" font="default" size="100%">Analele Stiintifice ale Universitatii &quot;Alexandru Ioan Cuza&quot; din Iasi Sec. II a. Genetica si Biologie Moleculara... now... Journal of Experimental and Molecular Biology (J. Exp. Molec. Biol.)</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.jemb.bio.uaic.ro/old_pdfs/2017/1/03Ajayi%20REbuilt%20July17%20numbered.pdf</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">17-23</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span&gt;This work describes a study carried out to determine the antioxidant properties, xanthine oxidase and pancreatic lipase inhibitory potential of crude ethanol extract of &lt;em&gt;Manihot esculenta&lt;/em&gt; matured leaf, in vitro. Antioxidant potential of the extract was ascertained using the 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and the nitroblue tetrazolium (NBT) assays. Xanthine oxidase (XO) inhibitory potential of the ethanol extract was assayed spectrophotometrically using a continuous time scan mode at 293 nm under aerobic condition; while porcine lipase was employed for the determination of its lipase inhibitory activity. The extract showed moderate antioxidant activity against DPPH (40.42±0.43%) and promising superoxide scavenging activity against NBT (94.76±0.44%) compared to different standard antioxidants including butylated hydroxylanisole (BHA), uric acid (UA), curcumin (CUR) and ascorbic acid (ASC). This extract showed mild (50.70±0.48%) xanthine oxidase inhibitory activity in comparison to allopurinol (92.1±0.35%), standard inhibitor of XO. Inhibition of porcine pancreatic lipase by Manihot esculenta leaf extract was significantly lower than that of the standard drug, Orlistat (67.53±0.22% and 94.81±0.78%, respectively). The results demonstrated that &lt;em&gt;Manihot esculenta&lt;/em&gt; leaf extract is a promising source of antioxidants, xanthine oxidase and pancreatic lipase inhibitory agents.&lt;/span&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record></records></xml>